Criteria of the dutch clinic network and genetic testing in familial hyperlipidemiae in a group of colombian patients

Abstract

Introduction: hyperlipidemia is a group of diseases, both hereditary and acquired, characterized by elevated levels of lipids in the human body, especially prevalent in the western hemisphere. Methods: this study seeks to identify patients with familial hyperlipidemia using the criteria of the Dutch Clinical Network applied to the subsidized population of Bucaramanga, Colombia, and evaluate their individual profiles. Results: the prevalence of heterozygous familial hypercholesterolemia (HeFH) is estimated to be 1 in 200 to 500 people, while the prevalence of homozygous familial hypercholesterolemia (HoFH) is 1 in 300,000 to 600,000 people. In Bucaramanga, it is projected that 240,000 people could have HeFH and from 160 to 300 cases of HoFH. Conclusions: despite the estimates, the real prevalence of the disease in Colombia is unknown, which justifies carrying out this study to obtain more precise data on familial hyperlipidemia in the region.